Sunday, April 30, 2017
Scientists confirm that they have grown the first working 'mini-brains' in a dish which could provide future treatments for autism and epilepsy.The lab-grown organs have their own brain cells, formed into circuits similar to those of a two-month-old baby in the womb. Repots indicate that is the first time a human forebrain has been seen in action outside the body.
Despite ones position on these matters, the creation is scientifically thrilling nonetheless. The Daily Mail reports that scientists hope to use the mini-brains to watch in real time the triggers for epilepsy, when brain cells become hyperactive, and autism, where they are thought to form bad connections. Scientists have grown the first working 'mini-brains' in a dish which could provide future treatments for autism and epilepsy.
The brains in a dish are the latest advance for stem cell science. Human skin cells are transformed into pluripotent stem cells, capable of becoming any part of the body, using four genes in a petri dish. The 'culture', or nutrient-rich broth they are grown in, is then altered to determine which type of cell they will become – in this case brain cells, or neurons.
The result is a 60-day old forebrain like a baby's in the womb, although more scrambled in its connections. It includes the cerebral cortex, the most highly evolved 'thinking' and decision-making part of the brain.
It could pave the way for drugs to treat these conditions, as well as schizophrenia. It is also the next step towards a real-life Frankenstein, suggesting scientists may one day be able to grow an entire human body in the laboratory. Researchers at Stanford University grew two forebrain circuits, measuring only a sixteenth of an inch across, using only human skin cells.Then scientists at Harvard University went a step further, growing a mini-organ for more than nine months to create a human retina – the light-sensitive lining at the back of the eye.
Dr Selina Wray, Alzheimer's Research UK senior research fellow at UCL Institute of Neurology, said: 'This technology will provide researchers with insights into brain development and disease which have not previously been possible.'
Dr Sergiu Pasca, assistant professor of psychiatry and behavioral sciences at Stanford University, said:
'We've never been able to recapitulate these human-brain developmental events in a dish before.
Dr Francois Guillemot, group leader and head of division of molecular neurobiology at the Francis Crick Institute in London, said the 'self-organising' ability of stem cells to become brain cells was 'remarkable'.
He said: 'I would not call these studies game-changers because previous organoid papers had already hinted at this. However they represent large steps forward. This is after all the first time that human neural circuits can be observed in action.'
Back in 2013 a similar scientific breakthrough made headlines. That research however, seems to have been a long way from the working "mini brains" scientists at Harvard University have just revealed.
The Daily Mail / TRUNEWS summary.
See more at: http://www.trunews.com/article/first-working-mini-brains-in-a-dish#sthash.wb9jMBNu.dpuf
Credit to Zero Hedge
Saturday, April 29, 2017
Compelling Evidence of the Incursions of Giants, Their Extraordinary Technology, and IMMINENT RETURN Part #3
Credit to Tom Horn
Friday, April 28, 2017
Obama launched a war in Libya in 2011, with the end result being that the nation has become increasingly hostile to Christianity. News in late April revealed that Islamic terrorists have driven many Christians from the country while the rest fear for their lives.
Obama’s war first overthrew Libyan leader Moammar Gadhafi, with U.S.-backed forces eventually sodomizing him before summarily executing him. The nation has essentially been lawless since then, with Islamic terrorists gaining increasing influence and control over it. This in turn has led to increasing attacks on Christians.
Breitbart reported on April 20 that the attacks on Christians have become so bad that some people now believe Libya has “lost the Christian presence.” The same Breitbart post also cited numbers claiming that somewhere around 20,000 Christians now live in Libya whereas “as many as 100,000” had lived there prior to the American-backed war.
Obama’s hatred of Christianity is one of the defining attributes of his presidency. Domestically, he attacked the free speech of Christians through Obamacare, the IRS, other government force, and as the leader of the cultural War on Christianity. His intense hatred of God was also why he advocated so hard for the twin evils of infanticide and sodomy. So a war in a foreign land that devastated Christianity in the process isn’t surprising.
Furthermore, such warring isn’t unique to Obama. It has in fact become a bipartisan and perpetual policy of the United States of America. George W. Bush launched wars in Afghanistan and Iraq. They ultimately led to a staggering loss of Christians in those nations as well. Indeed, even as the Ruling Class has accused the U.S. of being on a crusade against Islam over the past 16 years, the reality is that the U.S. has been on a jihad against Christianity.
Christianity is nearly nonexistent in Afghanistan today, and many fear it will disappear from Iraq. Obama’s war in Libya means its survival is threatened there as well.
Credit to Barbwire.comhttp://barbwire.com/2017/04/28/obamas-war-in-libya-has-devastated-christianity/
Have you ever wondered how tech companies that have been losing hundreds of millions of dollars year after year can somehow be worth billions of dollars according to the stock market? Because I run a website called “The Economic Collapse“, there are naysayers out there that take glee in mocking me by pointing out how well the stock market has been doing. This week, the Dow is flirting with 21,000 and the Nasdaq crossed the 6,000 threshold for the first time ever. But a lot of the “soaring stocks” that have been fueling this rally have been losing giant mountains of money every single year, and just like the first tech bubble this madness will eventually come to an end in a spectacular fiery crash in which investors will lose trillions of dollars.
Anyone that cannot see that we are in the midst of an absolutely insane stock market bubble simply does not understand economics. Every valuation indicator that you can possibly point to says that we are in a bubble of epic proportions, and history teaches us that all bubbles inevitably come to an end at some point.
Earlier today, I came across an article by Graham Summers in which he persuasively argued that the price to sales ratio indicates that stock prices are far more inflated than they were just prior to the great stock market crash of 2008…
Sales cannot be gimmicked. Either money comes in the door, or it doesn’t. And if a company is caught messing around with its sales numbers, someone is going to jail.For this reason, Price to Sales is perhaps the single most objective and clear means of measuring stock valuations.This metric, above all others, you can point to and say, “this is definitively accurate and has not been messed with.”On that note, as Bill King recently noted, today the S&P 500 is sporting a P/S ratio that is massively higher than it was in 2007 and is only marginally lower than it was during the Tech Bubble (the single largest stock bubble of all time for most measures).
To me, looking at profitability is even more important than looking at sales.
Large tech companies such as Twitter certainly have lots of revenue coming in, but many of them are deeply unprofitable.
In fact, Twitter has never made a yearly profit, and over the past decade it has actually lost more than 2 billion dollars.
But despite all of that, investors absolutely love Twitter stock. As I write this article, Twitter has a market cap of 11.5 billion dollars.
How in the world is that possible?
How can a company that has never made a single penny be worth more than 11 billion dollars?
Twitter is never going to be more popular than it is now. If it can’t make a profit at the peak of its popularity, when will it ever happen?
And guess what? ABC News says that Twitter actually just reported a decline in revenue for the most recent quarter…
Twitter has never turned a profit, and for the first time since going public in 2013, it reported a decline in revenue from the previous year. Its revenue was $548.3 million, down 8 percent.Net loss was $61.6 million, or 9 cents per share, compared with a loss of $79.7 million, or 12 cents per share, a year earlier.
The only reason why financial black holes such as Twitter can continue to exist is because investors have been willing to pour endless amounts of money into them, but now that bubble is starting to burst.
In his most recent article, Simon Black discussed how Silicon Valley investors are starting to become more cautious because so many of these “unicorns” are now going bust. One of the examples that he cited in his article was a company called Clinkle…
(Given that investing in an early stage company is high-risk, investors might provide a few hundred thousand dollars in funding, at most. Clinkle raised $25 million.)The company went on to burn through just about every penny of its investors’ capital.There were even photos that surfaced of the 21-year old CEO literally setting bricks of cash on fire.At the end of the farce, Clinkle never actually managed to build its supposedly ‘world-changing’ product, and the website is now all but defunct.
Most of you may have never even heard of Clinkle, but I bet that you have definitely heard of Netflix.
Netflix has revolutionized how movies are delivered to our homes, and that revolution helped drive movie rental stores to the brink of extinction.
There is just one huge problem. It turns out that Netflix is losing hundreds of millions of dollars…
Netflix might be my favorite example.The company’s most recent earnings report for the period ending March 31, 2017 shows, yet again, negative Free Cash Flow of MINUS $422 million.Not only is that a record loss, it’s 62% worse than in Q1/2016, and over twice as bad as Q1/2015.Netflix just keeps losing more and more money.
But even though Netflix is losing money at a pace that is exceedingly difficult to imagine, investors absolutely love the company.
I just checked, and at this moment Netflix has a market cap of 68.4 billion dollars.
Sometimes I just want to scream because of the absurdity of it all.
Companies that are losing hundreds of millions of dollars a year at the peak of their popularity should not be worth billions of dollars.
Nobody can possibly argue that these enormously inflated stock prices are sustainable. Just like with every other stock market bubble in our history, this one is going to burst too, and I have been warning about this for quite a long time.
But for the moment, the naysayers are having their time to shine. Despite the fact that U.S. consumers are 12 trillion dollars in debt, and despite the fact that corporate debt has doubled since the last financial crisis, and despite the fact that the federal government is 20 trillion dollars in debt, they seem to be convinced that this irrational stock market bubble can keep inflating indefinitely.
Perhaps they can all put their money where their mouth is by pouring all of their savings into Twitter, Netflix and other tech company stocks.
In the end, we will see who was right and who was wrong.
Credit to Economic Collapse